Non-pharmacological treatments for orthostatic hypotension

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Non-pharmacological treatments for orthostatic hypotension.

In a recent issue of Age and Ageing, Fan et al. report negative results in a randomised controlled trial on the use of sleeping in the head-up position (SHU) in the treatment of orthostatic hypotension (OH) [1]. We ask if this treatment or other non-pharmacological therapies should be recommended for use in elderly patients? Postural or Orthostatic Hypotension is a common clinical problem affec...

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Efficacy of treatments for orthostatic hypotension: a systematic review.

BACKGROUND orthostatic hypotension (OH) affects up to 30% of adults over 65 and frequently contributes to falls and syncopal episodes. Current guidelines suggest a wide range of treatments, but systematic reviews of the evidence base for such recommendations are lacking. METHODS we performed a systematic review to assess the evidence for all non-pharmacological and pharmacological interventio...

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Orthostatic hypotension.

A 29-year-old white woman (weight, 1211b; height, 5 ft 6 in.) was referred to the Hypertension Unit of Massachusetts General Hospital in December 1984. She had been athletic and apparently in excellent health until September 1979 when she contracted an upper respiratory tract infection associated with wheezing. She was treated with prednisone for 5 days with resolution of the symptoms but later...

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Droxidopa for neurogenic orthostatic hypotension

OBJECTIVE To determine whether droxidopa, an oral norepinephrine precursor, improves symptomatic neurogenic orthostatic hypotension (nOH). METHODS Patients with symptomatic nOH due to Parkinson disease, multiple system atrophy, pure autonomic failure, or nondiabetic autonomic neuropathy underwent open-label droxidopa dose optimization (100-600 mg 3 times daily), followed, in responders, by 7-...

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Neurogenic Orthostatic Hypotension

n engl j med 358;6 www.nejm.org february 7, 2008 615 A 65-year-old man reports a 6-month history of dizziness, light-headedness, weakness, and fatigue while upright. He takes no medication and has no personal or family history of neurologic disease. On physical examination, his supine blood pressure is 160/100 mm Hg, with a heart rate of 72 beats per minute; on standing, his blood pressure fall...

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ژورنال

عنوان ژورنال: Age and Ageing

سال: 2011

ISSN: 0002-0729,1468-2834

DOI: 10.1093/ageing/afr036